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OPEN Foundation

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OPEN is a Dutch foundation that seeks to encourage interdisciplinary research into psychedelics.

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ICPR 2012

Upcoming fall brings OPEN's second conference: Interdisciplinary Conference on Psychedelic Research.

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Volunteer!

Do you have a fascination for psychedelics? OPEN Foundation is looking for volunteers!

Join us

Latest news

  • May 02, 2012

    First Names Public

    We are happy to announce some of the speakers of our conference. At the Interdisciplinary Conference on Psychedelic Research 2012 you can hear Dr. Robin Carhart-Harris, Dr. Matthew W. Johnson, Dr. Robin MacKenzie, Prof. dr. Wouter Hanegraaff. Read more

  • February 16, 2012

    Psychedelic research in popular literature

    The Dutch KIJK magazine printed an article on research on psychedelics. “Tripping away your problems: a slow revival of drugs as medicine”. Reporter Jop de Vrieze interviewed scientists among whom psychiatrists Andrew Feldmár en Charles Grob... Read more

  • January 29, 2012

    New study may explain magic mushrooms' effects

    New research by a group of mainly Britisch scientists, based on fMRI brain scans, has shown that the use of psilocybin (the active constituent of magic mushrooms) decreases the activity of certain parts of the brain in test subjects. Read more

  • December 29, 2011

    Ayahuasca Scientific Literature Overview

    In response to the claims made in a 2010 communication with ICEERS by the United Nations International Narcotics Control Board regarding the 'serious health risks' associated with the intake of Ayahuasca, Psychologist and Ayahuasca... Read more

  • October 24, 2011

    Magic mushrooms can improve mental health

    According to new research by the Johns Hopkins School of Medicine in Baltimore, magic mushrooms can have long-lasting positive effects on people's well-being. After their use of the drug, volunteers reported positive effects such as... Read more

  • October 22, 2011

    Pre-announcement Mind Altering Science 2012

    OPEN is busy organising its second scientific conference on psychedelic research in the weekend of June 1-3: Mind Altering Science 2012. You can expect the latest results on research into MDMA, psilocybin, ayahuasca, LSD, ketamine ... Read more

  • September 15, 2011

    EARS Researcher Workgroup Report by MAPS Hungary

    In April 2011, over 300 people convened at the University of Amsterdam to attend the European Ayahuasca Research Symposium, a half-day seminar co-sponsored by The OPEN Foundation and MAPS. The Symposium brought... Read more

  • August 01, 2011

    Grant for new research on the positive effects of XTC

    Two neuropsychologists from the University of Maastricht, Jan Ramaekers and Kim Kuypers, have been granted €200.000 from the NWO, the Netherlands Organisation for Scientific Research. This will allow them to buy plenty of pills for... Read more

  • July 26, 2011

    EARS report by Simon Powell

    Last month in Amsterdam we held the European Ayahuasca Research Symposium, a one-day lecture series exploring the current state of research into the medical, therapeutic, and spiritual uses of ayahuasca. Simon Powell, author of... Read more

  • May 19, 2011

    European Ayahuasca Research Symposium

    The European Ayahuasca Research Symposium is a multidisciplinary series of lectures that focuses on current research being done in Europe. Experts from different disciplines will present their studies on ayahuasca’s effects on health... Read more

  • May 16, 2011

    LSD documentary night Amsterdam

    The LSD documentary night returns, this time to our hometown Amsterdam. This evening features two documentaries: Hofmann's Potion and LSD: Problem Child and Wonder Drug. Both documentaries offer a special view on one of... Read more

  • May 05, 2011

    Rick Strassman Interview

    Weblog boingboing has published an interview with psychiatrist Rick Strassman. He was the first scientist to conduct U.S. government-approved human research into hallucinogens and psychedelic drugs after the so-called... Read more

  • April 18, 2011

    Wanted: participants for survey

    Do you take drugs to heighten your spirituality? Read on! We are looking for participants for a new survey regarding the relationship between drugs and spirituality. The research focuses on all kinds of drugs, from alcohol and cocaine to LSD. Read more

  • April 11, 2011

    Psilocybin cuts brain blood flow and connections

    Psychedelic drug users throughout the ages have described their experiences as mind-expanding. They might be surprised, therefore, to hear that psilocybin – the active ingredient in magic mushrooms – actually decreases blood flow... Read more

  • March 28, 2011

    Medical Psychedelics - Soma for the masses?

    Are psychedelics and entheogens medicines and/or spiritual tools for consciousness expansion? Can they be culture jammed by Big Pharma into commodified weapons of mass control, a soma for the masses? Find out the answers as... Read more

  • March 18, 2011

    Prehistoric mushroom use in Spain

    Europeans may have used magic mushrooms to liven up religious rituals 6000 years ago. So suggests a cave mural in Spain, which may depict fungi with hallucinogenic properties - the oldest evidence of their use in Europe. The Selva... Read more

  • March 12, 2011

    New website launched

    After months of hard work, it is finally finished: our completely renewed website. A cleaner layout, improved navigation and many new features: search functionality, the option to view the website in English, a video library with recordings of OPEN... Read more

  • March 10, 2011

    New Shulgin book published!

    We mentioned it earlier on our website, a new book by Alexander Shulgin (from PiHKAL and TiHKAL) was on its way. And now, the moment has arrived! The Shulgin Index, the new book by Alexander Shulgin, Tania Manning and... Read more

  • March 09, 2011

    Salvia and psychopharmacology

    Salvia, with the active component Salvinorin A, has been awell-known recreational drug for years and can be found in smart shops, but is also used in for instance Mexico because of its spiritual properties. On our website... Read more

  • February 28, 2011

    An honest look at the risks and benefits of MDMA

    Addiction, one of the most important peer-reviewed journals on drug use and abuse, has published the results of a study regarding the use of recreational ecstacy use and potential cognitive damage - which turned out to be absent. The study is... Read more

  • January 21, 2011

    Mind Altering photos and cartoons online

    Photos from our Mind Altering Science conference are finally available. Recapture your memories in the new photo gallery on the MAS website. The cartoons by Margreet de Heer and Yiri Kohl are available as well, you can find them here... Read more

  • December 15, 2010

    International drug survey

    The Beckley Foundation has started an online survey regarding the pros and cons associated with drug, including alcohol and nicotine. And you can join in! It is completely anonymous and will, according to its designers, contribute to a thorough revision of... Read more

  • December 15, 2010

    Finance psychedelic research by watching videos

    A sponsor has promised the American organisation MAPS (Multidisciplinary Association for Psychedelic Studies) $1 every time someone watches one of their videos, up to a maximum of $15.000. Read more

  • November 30, 2010

    Psilocybin study leads to spiritual experience

    A participant of a survey regarding the effect of psilocybin on the brain explains what spiritual experiences she had in this interesting article. 62-year-old Maria Estevez took part in a survey that wanted to see how hallucinogenics work. She describes how... Read more

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New books

  • March 17, 2011

    The Ethnopharmacology of Ayahuasca

    This free e-book by Rafael Guimarães dos Santos brings together papers on the anthropology, pharmacology, psychology and psychiatry of ayahuasca. It has contributions by some of the main ayahuasca researchers like Jose Carlos Bouso... Read more

  • March 11, 2011

    Psychedelic Information Theory

    “Psychedelic Information Theory: Shamanism in the Age of Reason,” is an analysis of the physical mechanisms underlying hallucination, shamanic ritual, and expanded states of consciousness. Written by James L. Kent... Read more

  • January 13, 2011

    The Beyond Within

    The Beyond Within of Sidney Cohen is a true LSD classic. Praised by Alan Watts, commended by Time in 1964 and now available online, for free.
    Read more

  • December 10, 2010

    The Psychedelic Journey of Marlene de Rios

    Marlene Dobkin de Rios has been a pioneer for 45 years when it comes to researching hallucinogens in Peru and the Amazon. Her study of ayahuasca is focused on using the substance in treating psychological and emotional disorders. She also... Read more

  • December 10, 2010

    Brazillian Ayahuasca Music

    Authors Bia Labate en Gustavo Pacheco have written a book on the central role and meaning of music with ayahuasca religions such as the Santo Daime Uniao do Vegetal. By comparing both religions, the authors want to understand the ethos... Read more

  • October 14, 2010

    From Medicine Men to Day Trippers

    An interesting thesis has been written on the phenomenon of ayahuasca tourism, by Evgenia Fotiou. In her thesis, she takes a look at the boundaries between experimenting, becoming initiated and spiritual use. She wonders... Read more

  • September 22, 2010

    Ayahuasca, Ritual and Religion in Brazil

    Bia Labatte and E. MacRae are publishing the book "Ayahuasca, Ritual and Religion in Brazil" together, in cooperation with publishing house Equinox (London). One of the chapters was written by lawyer Domingos Bernardo de Sá... Read more

  • September 21, 2010

    Shamanism (Michael Winkelman)

    Michael Winkelman has already written the book Shamanism (2000) and now he has published Shamanism: A Biopsychosocial Paradigm of Consciousness and Healing. This is a second, rewritten and improved print of the first book... Read more

  • July 23, 2010

    The Pharmacology of LSD: A critical review

    LSD has a controversial and special reputation due to its special effect on the consciousness. Experimental use has brought about trail-blazing discoveries about the brain and the deeper layers of the human psyche. Today, a new interest in LSD... Read more

  • June 17, 2010

    The Shulgin Index

    The time has finally come: the new book of Alexander "Sasha" Shulgin is on its way. The author is known for his pioneering work regarding phenylethylamine and tryptamine, and has established himself with books like PiHKAL and TiHKAL... Read more

  • December 03, 2009

    LSD: The highway to mental health

    The book describes the work of Dr. Milan Hausner at his clinic at Sadska, near Prague, where as Medical Director of the psychiatric clinic he supervised over 3,000 LSD therapeutic sessions from 1954 to 1980. As Grof says on a back cover blurb... Read more

New videos

  • April 28, 2012

    Mind Altering Science: Torsten Passie

    Dr. Passie completed his training as a specialist in psychiatry and psychotherapy as well as his academic work at the Psychiatric University Hospital Zurich, in practice by Prof. Hans Carl Leuner in Göttingen and Hannover Medical School. Watch here

  • April 20, 2012

    Mind Altering Science: Joe Bicknell

    Psychedelic phenomenology deals with the phenomenal content of psychedelic tripping, thus phenomenology approaches psychedelics from the reverse direction of the scientific approach, because instead of looking at the structures of physical... Watch here

  • April 20, 2012

    Mind Altering Science: David Luke

    The Amazonian sacramental decoction, ayahuasca (containing an alkaloid once called telepathine by Westerners), has been used by indigenous shamans and healers for several millennia. Apparently, for the explicit purposes of accessing altered states... Watch here

  • April 20, 2012

    Mind Altering Science: Konstantin Kuteykin-Teplyakov

    Molecules of mysticism” are chemical substances that are able to induce mystical experience, increasing the feeling of closeness to the god (entheogens) or to other people (empathogens). It is quite likely, that every mystical experience is mediated... Watch here

  • March 30, 2012

    Mind Altering Science: Klaas Pieter van der Tempel

    How does the psychedelic experience affect the knowledge and motivation of the scientist? And what does this mean for academia in general? To answer such questions, this presentation will focus on the master's thesis... Watch here

  • October 22, 2011

    Mind Altering Science: Jazmin Wuyts

    In 2007, as part of the MA Cultural Anthropology, I have done research amongst the members of the Santo Daime church in Florianópolis (Brazil) and in The Hague. In their ceremonies they use ayahuasca, sometimes combined with cannabis... Watch here

  • October 22, 2011

    Mind Altering Science: Anwar Jeewa

    It has become increasingly difficult to assist an individual to maintain long term recovery from substance abuse. This is frustrating to individuals, their families and also to service providers. The reason for this trend is not absolutely clear. Over... Watch here

  • October 22, 2011

    Mind Altering Science: Katharina Kirchner

    After more than 40 years the first study employing LSD in psychotherapy is being conducted in Switzerland. 12 persons suffering from a life-threatening disease and an anxiety disorder are having the possibility to receive 200µg of LSD in a... Watch here

  • August 24, 2011

    Mind Altering Science: Stephen Whitmarsh

    In 2009 we traveled to the Peruvian Jungle to participate in ayahuasca ceremonies with renowned Shipibo shaman Don Guillermo Arévalo. Our research goal was to investigate the neural correlates of the psycho-therapeutic and... Watch here

  • August 24, 2011

    Mind Altering Science: Andrew Sewell

    Human psychopharmacology--the experimental administration of mind-altering drugs to human subjects--is an essential tool for characterizing the relationship between brain structure, neurochemistry, and symptomatology. This talk will... Watch here

  • July 30, 2011

    Mind Altering Science: Ruud Litjens

    Ibogaine has been used for centuries by members of the Bwiti religion in western equatorial Africa as a religious sacrament, medicine and hunting aid. Since the discovery of the ability of ibogaine to interrupt addiction and... Watch here

  • July 30, 2011

    Mind Altering Science: Jacqueline Braak

    In literature much can be found about the visions and the insights people can get from ayahuasca. What is striking here is that the visions are described in great detail while the insights only marginally are mentioned. This lack of information... Watch here

  • July 30, 2011

    Mind Altering Science: Daniel Waterman

    The revival of psychedelic research signals an inspiring change in official attitudes towards 'mind-altering' substances, altered states of consciousness and their potential as catalysts of religious/mystical experience, 'self-healing'... Watch here

  • July 30, 2011

    Mind Altering Science: Adèle van der Plas

    This presentation will examine the legal aspects of the use of ayahuasca. No plants or other natural materials containing psychoactive substances like DMT or psilocybin are controlled under the UN 1971 Convention. The same... Watch here

  • July 30, 2011

    Mind Altering Science: Stephen Snelders

    In the year 2010 hopeful prospects are attached to psychotherapy with hallucinogens. Attempts are made to bring this kind of therapy out of the confines of illegal subcultures and into legalized medical settings. Discussions and arguments center... Watch here

  • March 18, 2011

    Ancient Drugs

    Join Dr. Andrew Weil and other leading physicians and scholars in this often-surprising look at the long history of drug use in different cultures worldwide Since mankind's beginning, in every civilization, human beings have found ways to alter their... Watch here

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Newsletter

OPEN Agenda

MAY
19

19.05.2012
OPEN Office

JUN
05

05.06.2012 20:00 - 23:30
OPEN borrel - East of Eden

Full agenda

Recent publications

Lysergic acid diethylamide (LSD) for alcoholism: meta-analysis of randomized controlled trials

Assessments of lysergic acid diethylamide (LSD) in the treatment of alcoholism have not been based on quantitative meta-analysis. Hence, we performed a meta-analysis of randomized controlled trials in...

Drugs as instruments: A new framework for non-addictive psychoactive drug use

Most people who are regular consumers of psychoactive drugs are not drug addicts, nor will they ever become addicts. In neurobiological theories, non-addictive drug consumption is acknowledged only as...

Psychedelic Experience as a Heuristic Tool for Exploring the Mind and the Brain

I discuss the ontological nature and heuristic value of psychedelic experience. I argue that psychedelic phenomena may manifest the activity of certain mental formations and brain mechanisms that otherwise...

Neural correlates of the psychedelic state as determined by fMRI studies with psilocybin

Psychedelic drugs have a long history of use in healing ceremonies, but despite renewed interest in their therapeutic potential, we continue to know very little about how they work in the brain. Here we...
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