Nederlandse samenvatting volgt nog, hier alvast een abstract in het Engels over dit artikel dat de risico's, veiligheid en preventieve maatregelen bespreekt, betreffende onderzoek naar hallucinogenen/psychedelica in mensen. Het oorspronkelijke artikel kunt u HIER vinden.

There has recently been a renewal of human research with classical

hallucinogens (psychedelics). This paper first briefly discusses the unique

history of human hallucinogen research, and then reviews the risks of

hallucinogen administration and safeguards for minimizing these risks.

Although hallucinogens are relatively safe physiologically and are not

considered drugs of dependence, their administration involves unique

psychological risks. The most likely risk is overwhelming distress during

drug action (‘bad trip’), which could lead to potentially dangerous

behaviour such as leaving the study site. Less common are prolonged

psychoses triggered by hallucinogens. Safeguards against these risks

include the exclusion of volunteers with personal or family history of

psychotic disorders or other severe psychiatric disorders, establishing trust

and rapport between session monitors and volunteer before the session,

careful volunteer preparation, a safe physical session environment and

interpersonal support from at least two study monitors during the session.

Investigators should probe for the relatively rare hallucinogen persisting

perception disorder in follow-up contact. Persisting adverse reactions are

rare when research is conducted along these guidelines. Incautious

research may jeopardize participant safety and future research. However,

carefully conducted research may inform the treatment of psychiatric

disorders, and may lead to advances in basic science.

Bron: Johnson, MW., Richards, WA, Griffiths, RR,  "Human Hallucinogen Research: Guidelines for Safety". J Psychopharmacol. Aug 2008;22(6):603-20.