Psilocybin-assisted therapy shows promising results for treatment-resistant depression

In a new study, the research team at the Imperial College London has tested the potential of psilocybin-assisted therapy to alleviate treatment-resistant depression. Statistics show that 20% of people suffering from major depression are unresponsive […]

DMT: Beyond the trip, a potential multifaceted medicine

N,N-dimethyltryptamine, more commonly known as DMT, is an exceptionally fast-acting and powerful psychedelic. DMT can be ingested by drinking the entheogenic brew ayahuasca, injected intravenously, intramuscularly or through inhalation. It is produced endogenously in a […]

Brain imaging reveals the action of LSD on the human brain

Once again researchers from the Psychedelic Research Programme jointly set up by the Beckley Foundation and Imperial College London have published trailblazing research on the effects of psychedelics on the brain. These trendsetting studies are […]

Psychedelic medicine: a re-emerging therapeutic paradigm

In a recent article, Tupper et al. (2015) investigate the new and re-emerging therapeutic paradigm involving psychedelic substances for treating mental health conditions. Recent studies with patient populations are reviewed and thoughts on how […]

Does LSD enhance the emotional response to music?

Aside from its hallucinogenic properties, LSD is known to have noticeable effects on emotion. This is one of the reasons why psychedelics were used in psychotherapy in the 1950s and 60s, hypothesizing that they facilitate […]

Ketamine-induced state models schizophrenia

In the 1950’s, research on the psychoactive properties of lysergic acid diethylamide (LSD) led scientists to the serotonin hypothesis of schizophrenia, a theory still used to explain the neurochemical roots of schizophrenia. Today, Höflich […]

Second part of special issue compiled by OPEN published

At the end of last month we published the first part of a special issue on the beneficial effects of psychedelics in the treatment of addiction of the scientific journal CDAR. Now, the second part […]

Special issue compiled by OPEN published in scientific journal

The OPEN Foundation is proud to announce that we compiled two special issues of the journal CDAR (Current Drug Abuse Reviews). The title of the Special Issues is ‘Beneficial Effects of Psychedelics with a Special […]

Classic psychedelic use is associated with reduced psychological distress and suicidality

In a population-based survey study that was published earlier this month, an association was found between the use of classic psychedelics and reduced psychological distress and suicidality . The researchers included the data of 191.382 […]

Sustained subjective benefits of LSD for the treatment of end-of-life anxiety

Earlier, we reported on the first study with LSD in human subjects in more than forty years, conducted in Switzerland by Peter Gasser and his team. A follow-up of this study , based on qualitative […]